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Image Search Results
Journal: American Journal of Translational Research
Article Title: CDKN2B-AS1 promotes the proliferation, clone formation, and invasion of nasopharyngeal carcinoma cells by regulating miR-98-5p/E2F2 axis
doi:
Figure Lengend Snippet: miR-98-5p is a target of CDKN2B-AS1. A: The common miRNA binding sites on CDKN2B-AS1 predicted by starBase and lncRBase; B: Subcellular localization of CDKN2B-AS1 detected by FISH assay (400×); C: miR-98-5p binding sites on CDKN2B-AS1; D: DLR assay results; E: RIP assay results; F: Expression levels of miR-98-5p in various tumors; G: Expression levels of miR-98-tp in the NPC tissues (n=38); H: ROC curve of miR-98-5p in the diagnosis of NPC; I: Correlation between the expression level of CDKN2B-AS1 and the expression level of miR-98-5p; J: Expression of miR-98-5p in the NPC cell line; K: Expression level of miR-980tp in NPC. Compared with the NP69 cell line, *P<0.05. CDKN2B-AS1: CDKN2B antisense RNA 1; NPC: nasopharyngeal carcinoma; OD: optical density; FISH: fluorescence in situ hybridization; DLR: dual-luciferase reporter; RIP: RNA immunoprecipitation.
Article Snippet: At 48 h of transfection, the luciferase activity of the NPC cells was detected using the
Techniques: Binding Assay, Expressing, Biomarker Discovery, Fluorescence, In Situ Hybridization, Luciferase, RNA Immunoprecipitation
Journal: American Journal of Translational Research
Article Title: CDKN2B-AS1 promotes the proliferation, clone formation, and invasion of nasopharyngeal carcinoma cells by regulating miR-98-5p/E2F2 axis
doi:
Figure Lengend Snippet: CDKN2B-AS1 sponges miR-98-5p to upregulate E2F2 expression. A: Expression level of E2F2 in head and neck squamous cell carcinoma reported by UALCAN database; B: Expression level of E2F2 in NPC tissues (n=38); C: Effect of silencing CDKN2B-AS1 on E2F2 expression; D: Effect of miR-98-5p overexpression on E2F2; E: Effect of silencing both miR-98-5p and CDKN2B-AS1 on E2F2; F: Correlation of E2F2 expression level with miR-98-5p expression level in NPC; G: Correlation of E2F2 expression level with CDKN2B-AS1 expression level in NPC; H: miR-98-5p binding sites on E2F2; I: DLR assay results; J: RIP assay results. CDKN2B-AS1: CDKN2B antisense RNA 1; NPC: nasopharyngeal carcinoma; OD: optical density; DLR: dual-luciferase reporter; RIP: RNA immunoprecipitation; E2F2: E2F transcription factor 2.
Article Snippet: At 48 h of transfection, the luciferase activity of the NPC cells was detected using the
Techniques: Expressing, Over Expression, Binding Assay, Luciferase, RNA Immunoprecipitation